Molecular Evolution and Phylogenetics

     The programs in lintre.unix.tar.Z are for (1) testing the molecular clock on a given topology of a phylogenetic tree and (2) making linearized trees (reestimating branch lengths under the assumption of constant rate of evolutions. The data that can be used are nucleotide or amino acid sequences.

     For details of the methods, please look at "Phylogenetic tests of the molecular clock and linearized trees" (Molecular Biology and Evolution 12:823-833, 1995).

(1) Ftp lintre.unix.tar.Z and lintre.unix.readme onto your system in the binary mode.
(2) Type "uncompress lintre.unix.tar.Z".
(3) Type "tar xvf lintre.unix.tar".
(4) Read the read.me file first.

     If you have problems or comments, please send email to:
      takezaki@med.kagawa-u.ac.jp

Sep 19, 1998

   Naoko Takezaki
   National Institute of Genetics
   1111 Yata, Mishima
   Shizuoka 411, Japan
   TEL: +81-559-81-6847
   FAX: +81-559-81-6848

     The programs for testing the molecular clock and making linearized trees are available by anonymous ftp at ftp.bio.indiana.edu. There are two files that you need to copy: lintre.unix.tar.Z and lintre-unix.readme. Please use binary mode for copying lintre.unix.tar.Z. If you have any problems or comments, let me know.

Current Address:

Naoko Takezaki
Information Technology Center

Kagawa University

1750-1 Ikenobe, Mikicho, Kitagun

Kagawa 761-0793

Japan
Email : takezaki@med.kagawa-u.ac.jp

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