Molecular Evolution and Phylogenetics

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| Average nucleotide diversity within and between populations|
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Introduction
NG-NEW is designed for estimating synonymous and nonsynonymous distances between protein coding DNA sequences. The method is modified from the original Nei and Gojobori (1986) method to take into account the transition bias. The program is written in C language and can be used on IBM PC compatible computers with the windows95 operating system.

sendbs is a program that computes average nucleotide substitutions within and between populations. The method is described in Nei and Jin (1989, MBE 6:290-300). However, note that sendbs computes standard errors of average nucleotide substitutions with a bootstrap method by resampling sites, which is different from Nei and Jin's method. Also, sensbs constructs a population tree with a neighbor-joining method.

(1) Ftp sendbsds.exe and sendbs.dos.readme onto your system in the binary mode.
(2) Type sendbsds.
(3) Read the read.me file first.

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Naoko Takezaki

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Kagawa University

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Kagawa 761-0793

Japan
Email : takezaki@med.kagawa-u.ac.jp

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